Zika, A new Outlook in Medicine?

zika

Its getting closer and closer to that time again. Its gradually warming and soon our favorite insects will be out and about once more: Mosquitoes….Last year Latin America and eventually parts of the United States were facing quite a vicious outbreak of a virus called Zika. This vector borne virus can be found in infected female mosquitos which go on to bite an individual and infect them with the virus.

This epidemic was becoming quite an epidemic and was part of the scary problem was if a pregnant woman was bitten, her child would experience microcephaly (meaning they would have a significantly smaller than normal head/brain size) which is a very concerning problem. Recently it would seem that the Western Hemisphere has actually come up with some type of vaccination and are actually looking to start with human clinical studies.

While this is really good for that we are trying to make a vaccine, researchers have speculations and wonder if the vaccinations will really help due to they will probably need Zika heavy areas to continue to see if what they are creating actually helps fend off from this nasty virus.  The current vaccine they want to test seems to be  made out of proteins found in mosquito saliva. The product is intended to trigger a human immune system response to the mosquito’s saliva and any viruses mixed with it.  The vaccine is currently going through or have just gone through Phase I trials.

The whole trials are a series of test and regulations to see if its safe before trial on humans and then its release to the whole public to be used. They aren’t quite sure if this whole outbreak last year is going to be yearly or if it was a one time explosion, but they are preparing. Scientist are also tracking the mosquito populations in states such as Texas. The one good thing that will come from this is that we will gain further knowledge and this may be able to help us with future vector borne viruses in the future.

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New Evidence to the Fall of an Ancient Latin America Empire

salmonella

The Aztec Empire, one of the most famous and most notable Empires in history especially throughout Latin America. It was dated to have first come about and around through what is now modern day Central America in the country of Mexico. The Empire was founded around 1428 and lasted roughly around a hundred years although this ancient group of people had quite a functional and one could argue a civilized empire. But how could a people who were fairly well adapted around this time have vanished after not being around for quite a century? That’s right you guessed it, it was due to the Europeans.

To be politically correct it was actually impart due to Conquistadors, or the explorers/conquerors for the Spanish Empire were the ones to have utterly crushed this empire, which was roughly estimated with a population to be as high as 25 million versus the small Spanish forces. It wasn’t so much  that the Europeans were better equipped and were more technologically advanced than the Natives that brought the Aztecs to their demise, it was actually due to a much smaller and more dangerous adversary…. a deadly form of Salmonella which came from Europe.

In a pair of recent studies, they have suggested and seemed to have found that from recovered DNA of the stomach bacterium from burials in Mexico which can be traced back to the 1540s, it is said that this caused an epidemic that wiped out up to 80% of the country’s native inhabitants. They traced this and look back to when Hernando Cortés a famous Spanish Conquistador came pretty much after a century helped plummet that population to 1 million. They believe one of the largest of the outbreaks, Cocoliztli killed many people and that in cities/large towns would big huge unmarked graves and dump the dead within them. microbiologistFrom this scientist gathered from using DNA and genetics to sequence DNA from 29 people buried and almost all were linked to Cocoliztli, and further sequencing of short damaged DNA showed and allowed the team to remake two genonmes of Salmonella enterica known as Paratyphi C. It is actually still found today and causes typhus like illness and is in most developing places, and if left untreated kills 10-15%.

Some things to consider is that modern medicine helps a lot and they didn’t have the same treatment to counter this threat. Also there is a question of origin which they think it came from Europe which if that is the case, this would leave the Natives to almost no immunity because they didn’t have contact with Europeans prior. Due to the lack of Sanitary conditions as well, this may have been a thriving source for Salmonella.

This is important because we have a better idea of what happened and can now trace ancient pathogens and the team looks to continue its findings and study other places such as in the Caribbean burial sites.